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Training -
An Introduction to Physiologically-Based Pharmacokinetic (PBPK) Modelling
 HSL is to run a one-day course covering the fundamental concepts
underlying physiologically based pharmacokinetic (PBPK) modelling.
The course will be held at the Health
and Safety Laboratory, Harpur Hill, Buxton, Derbyshire.
Dates
Please email your expression of interest
Introduction
The aim of this introductory course is to increase knowledge and
expertise in PBPK modelling as a tool for improving the predictive
value of chemical risk assessment. Designed to appeal to individuals
actively involved in the risk assessment processes, it will include
presentations by experts in the field.
What will the course cover?
• Use in human health risk assessment;
• Build PBPK models rapidly using a state of the art model
equation generator;
• Potential in the reduction and replacement of animals in
toxicological evaluation.
Upon completion of the course delegates will:
• Understand the need and value of modelling in general;
• Understand the fundamental concepts underlying PBPK modelling;
• Build PBPK models rapidly using a model equation generator
and visualize model output using Berkeley Madonna®
Who should attend?
Industrial professionals responsible for conducting or evaluating
risk assessments on consumer, environmental and occupational exposure
to chemicals; Occupational health and safety
professionals; Scientists interested in physiologically based pharmacokinetic
modelling.
Places will be limited to ensure active participation in the ‘hands-on
session’. Early registration is recommended.
Who will present?
Keynote Speaker, Professor Emeritus Malcolm Rowland - Malcolm
Rowland is Research
Professor and former Dean (1998-2001), School of Pharmacy and Pharmaceutical
Sciences, and former director, Centre for Applied Pharmacokinetic
Research (1996-2000), University of Manchester. His main research
interest is physiologically based pharmacokinetics and its application
to drug discovery and development. He is author of over 250 scientific
articles and chapters, and is co-author of the textbook - Clinical
Pharmacokinetics: Concepts and Applications. He is among the Thomson
ISI’s top 250 most highly cited pharmacologists worldwide.
He
is an editor of the Journal of Pharmacokinetics and Pharmacodynamics
(formerly Journal of Pharmacokinetics and Biopharmaceutics), and
has established European and U.S.A. workshops for teaching of both
basicand advanced pharmacokinetics.
Dr George Loizou - Head of the Computational Toxicology
Section at HSL.
Dr Martin Spendiff - Senior Mathematician in the Computational
Toxicology Section.
Venue
The Course will be run at the new HSL laboratory in the spa town
of Buxton. Buxton is in the heart of the Peak District and has good
links to mainline train stations and Manchester international Airport.
 To register online
please click here
For further information email: training@hsl.gov.uk or contact the Training Unit at HSL directly on 01298 218806.
Details
of hotels in the Buxton area can be found at http://www.visitpeakdistrict.com
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