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Introduction
| Fire, Explosion & Process
Safety | Human Factors
& Risk Assessment
Occupational & Environmental
Health | Safety Engineering |
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Services | Specialist
Scientific Facilities
Capabilities -
Occupational & Environmental Health
Bringing
together expertise in occupational medicine, biochemistry, analytical
toxicology, clinical chemistry, physiology, microbiology, immunology
and computer modelling. We provide a comprehensive service for the
investigation of workplace and environmental hazards and their consequences
on human health. Our work ranges from single investigations of exposure
to a chemical, biological or physical hazard through to large scale
surveys.
Case Studies
Our occupational and environmental health
capability encompasses:
- Biological Monitoring - measuring
individual exposure to organic chemicals, pesticides, metals and trace
elements in biological samples.
- Analytical and forensic toxicology.
- Sampling and identification of infectious, toxic and allergenic
microorganisms. Molecular biology and mobile laboratory facilities
are available.
- Microbiology. Category 3 containment microbiology facilities
are available.
- Human metabolism studies, including: dermal and inhalation uptake;
toxicokinetic studies.
- Health effects arising from toxic substances and physical agents,
including: development of early markers of organ damage; assessment
of biological, psychological and physiological changes caused
by external stressors.
- Occupational asthma.
- Occupational health assessment.
Clinical assessment of occupational lung disease is carried out
through the Centre for Workplace Health.
- Computational modelling using specialist toxicological applications,
including: physiologically-based pharmacokinetic
(PBPK) models; application of Bayesian statistics; structure-activity
relationships; expert systems for the prediction of toxicity and
skin penetration; mathematical modelling; modelling of population
variability.
- In-vitro toxicology, including: metabolism studies; percutaneous
absorption.
- Co-organiser of the UK Quality Assessment Scheme for metals
in blood.
Further Information:
Contact our Business Development Unit by telephone (+44) 01298 218218, fax (+44) 01298 218822 or email hslinfo@hsl.gov.uk.
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